A list of collaborations between actors in the Scream franchise, trivia details about the actors, and callbacks to related actors in the films themselves, as well as to that of the TV series, which encompasses crossovers outside and collaborations with that of both film and TV actors in other ventures.

Emma Roberts and Nico Tortorella working together on Twelve.

David Arquette and Drew Barrymore working together on Never Been Kissed.

Matthew Lillard and Sarah Michelle Gellar on Scooby-Doo.

Marisol Nichols (far right) and Rose McGowan on Charmed.

Neve Campbell and Skeet Ulrich on The Craft.

Emma Roberts and Rory Culkin together on Lymelife.
- Matthew Lillard from Scream (1996) and Sarah Michelle Gellar from Scream 2 (1997) later starred in Scooby-Doo (2002) together, and it's sequel (2004).
- Jada Pinkett Smith, Neve Campbell, Erik Knudsen and Hayden Panettiere who star in Scream were in the animated version of Scooby-Doo.
- Emma Roberts, Rory Culkin and Nico Tortorella all starred together in the movie Twelve (2010).
- Emma Roberts and Rory Culkin also starred together on Lymelife (2008), making Scream 4 their third movie collaboration. Emma's character also seduces Rory's character in that movie.
- Emma Roberts and Keke Palmer starred together in the FX show Scream Queens (2015-2016).
- Emma Roberts and Dermot Mulroney starred together in the seventh season of American Horror Story, subtitled Cult (2017).
- Alison Brie and Joel McHale both starred together in Community (2009-2015), and whose characters in the Scream franchise are close to Sidney Prescott: Brie as as Rebecca Walters, her publicist in Scream 4, McHale as her husband Mark Evans in the upcoming Scream 7.
- Rory Culkin and Paris Jackson star in the Amazon Prime miniseries, Swarm (2023), created by Donald Glover, the latter (also known by his musical stage name, Childish Gambino) most famous for his role as Troy Barnes from NBC's Community (2009-2015), of which he had co-starred alongside both Alison Brie and Joel McHale, his costars of who both are in the Scream franchise: Brie in Scream 4, and McHale in the upcoming Scream 7.
- Drew Barrymore and David Arquette were in Never Been Kissed (1999) together. The actors were friends from early childhood. The movie also starred Marley Shelton who later played Judy Hicks in Scream 4.
- Drew Barrymore and Bella Thorne starred in Blended (2014). Bella later portrays Nina Patterson in Season 1, whose character's death in the first episode and the opening scene of "Pilot" was an homage to that of Drew's performance as Casey from the first film.
- Dylan Minnette and Bella Thorne starred together in Alexander and the Terrible, Horrible, No Good, Very Bad Day (2014).
- In the first two Stab films, David Schwimmer portrays Dewey Riley. This is a reference to the fact that he stars with Courteney Cox on Friends.
- Actress Sharon Stone is referenced by name by Billy Loomis and Stu Macher in the original Scream, as well as her film Basic Instinct (1992) by Tatum Riley.
- Neve Campbell who plays Sidney Prescott and Matthew Lillard who plays Stu Macher, have dated once.
- Jada Pinkett Smith produced a show called All Of Us in which Elise Neal co-starred.
- Jada Pinkett Smith and David Schwimmer both voiced and starred in Madagascar (2005) as anthropomorphic animal characters Gloria the hippo (Smith) and Melman the giraffe (Schwimmer), who reprised their roles for its two sequels (2008-2012).
- Jada Pinkett-Smith starred in Magic Mike XXL (2015), alongside Channing Tatum, of who was referenced by name by Sherrie (Lucy Hale) in Stab 6 as shown in Scream 4.
- Jada Pinkett Smith starred in Girls Trip (2017) alongside Queen Latifah and Regina Hall.
- The former appearing and had co-starred in Scary Movie 3 (2003) alongside Regina Hall, Anthony Anderson, and Jenny McCarthy, as the latter two were Scream sequel characters (with McCarthy as Sarah Darling in Scream 3, who'd be succeeded by Anderson as Anthony Perkins in Scream 4), who'd then go on to be the executive producer of the third season of the TV series, Scream: Resurrection.
- The latter would portray Brenda Meeks, who parodied Jada's character Maureen Evans's death from Scream 2, in Scary Movie (2000).
- Courteney Cox and David Arquette also worked together on Friends.
- W. Earl Brown appeared in a 2001 episode of the television show, Charmed where Rose McGowan who played Tatum Riley, later starred in as played Paige Matthews.
- Rose McGowan was forced to dye her hair blonde for the role of Tatum Riley in order to look different then Neve Campbell, seeing that at the time they both had black hair.
- Shannen Doherty and Charisma Carpenter tried out for the role of Sarah Darling, but it eventually went to Jenny McCarthy.
- Ironically, Shannen was on Charmed also, however, she left the series before Jenny had a role three seasons later. Charisma also had a small recurring part on Charmed with Rose McGowan and was a main character on Buffy the Vampire Slayer, with Sarah Michelle Gellar.
- Marisol Nichols who plays Dawnie in Scream 2 was in Friends with
Rutina Wesley and Anna Paquin on True Blood.
- Marisol Nichols and Mark Consuelos starred together as Hermoine and Hiram Lodge, spouses, on the CW show Riverdale (2017-2023), with Consuelos being cast in Scream 7.
- Skeet Ulrich had also appeared in Riverdale alongside Nichols and Consuelos, alongside the late Luke Perry, who'd been both Tori Spelling and Shannen Doherty's co-star on Beverly Hills, 90210.
- Neve Campbell and Skeet Ulrich played opposite each other in The Craft, the same year Scream (1996) released.
- Rutina Wesley signed on for Scream 4 as Marcie Perkins, wife of Anthony Perkins (Anthony Anderson) before being dropped due to film budget cuts. Anna Paquin, her True Blood (2008-2014) co-star, had a role nonetheless as Rachel in the movie-within-a-movie of Stab 7. Anna Camp, who's cast in Scream 7, alongside Paquin and Wesley, was also in True Blood.
- Anna Paquin, Scott Foley, Anna Camp, and Amelia Rose Blaire all appeared on the HBO series True Blood.
- Neve Campbell had a recurring role on Medium, in which David Arquette's sister, Patricia, is the main star in.
- Anna Paquin and Adam Brody starred together in The Romantics (2010).
- Lucy Hale and Adam Brody worked together in The OC.
- Kristen Bell and Adam Brody starred in the Netflix rom-com series Nobody Wants This (2024).
- Kristen Bell and Sarah Michelle Gellar were featured on re-runs of each's respective shows as a back-to back, in 2013 on the TV network, Pivot in order to promote the network, with Bell as the titular character and name of the UPN/CW show, Veronica Mars (2004-2007), and Gellar also from her titular role as well and sharing the name of the WB/UPN show, Buffy the Vampire Slayer (1997-2003).[1]
- Hayden Panettiere and Kristen Bell starred together in the NBC series Heroes (2006-2010).
- In Scream 4, Olivia tells Jill and Kirby about Sidney being the angel of Death, and how Stab is the wrong franchise for her and that it should be Final Destination (2000-present).
- Ali Larter (once considered for the role of Sarah Darling), who would co-star alongside Panettiere and Bell in Heroes, starred in the first two Final Destination films (2000-2003), who co-starred with Tony Todd, who in the Scream franchise, had portrayed Luther Thompson in Season 3 (Scream: Resurrection, 2019) of the TV series, with Todd appearing in the first, second, fifth, and sixth films of the Final Destination franchise, to date.
- Bobby Campo, who portrayed Seth Branson in Season 1 to Season 2, portrayed the main protagonist Nick O'Bannon in The Final Destination (2009), the fourth film of the aforementioned franchise, which is also the only one which Todd didn't appear in, who had a voice role cameo in Final Destination 3 (2006).
- Erik Knudsen, who appeared as Robbie Mercer in Scream 4, regarding Olivia's comment on Final Destination, appeared in Scott Pilgrim vs. The World (2010), with Mary Elizabeth Winstead as Ramona Flowers, the latter having portrayed the protagonist Wendy Christensen in Final Destination 3, of which Todd appeared as a voice cameo role.
- Max Lloyd-Jones as Tyler O'Neill in Season 1, appears in the sixth film of the Final Destination franchise, Final Destination: Bloodlines (2025) as Paul Campbell, the husband of former protagonist Iris Campbell, of which Todd also appears in, posthumously (due to the actor's death in 2024).
Rose McGowan and Rebecca Gayheart working on Jawbreaker.
Rose McGowan and Jenny McCarthy on Charmed.
- Ali Larter (once considered for the role of Sarah Darling), who would co-star alongside Panettiere and Bell in Heroes, starred in the first two Final Destination films (2000-2003), who co-starred with Tony Todd, who in the Scream franchise, had portrayed Luther Thompson in Season 3 (Scream: Resurrection, 2019) of the TV series, with Todd appearing in the first, second, fifth, and sixth films of the Final Destination franchise, to date.
- Aimee Teegarden, Alison Brie and Nancy O'Dell were all in Hannah Montana.
- Rebecca Gayheart, Elise Neal, and Joshua Jackson starred together in the film Urban Legend (1998).
- Adam Brody, Kyle Gallner, and Lance Henriksen appear in Jennifer's Body (2009) together.
- Willa Fitzgerald and Kyle Gallner starred together in Strange Darling (2023).
- Sosie Bacon and Kyle Gallner starred in Smile (2022). Sosie's father, Kevin Bacon, was mentioned by name by Murphy in Scream 2.
- RJ Cyler who portrayed Marcus Elliot in Scream: Resurrection, starred in the 2017 Power Rangers film alongside Naomi Scott, the latter of who portrayed the titular role of Skye Riley in Smile 2 (2024), as the sequel to the first Smile which starred Sosie and Kyle, filling the titular protagonist role vacated after Sosie's character's death in the first.
- Coincidentally, Scott starred as Princess Jasmine in the 2019 live action Aladdin with Will Smith as The Genie, who is Jada-Pinkett's husband.
- Melissa Barrera starred in Abigail with Kathryn Newton, the latter of which had previously starred in the 2020 slasher, Freaky, alongside Vince Vaughn, with Celeste O'Connor also appearing.
- Vaughn shown as the actor in-universe to have in the first Stab portrayed Stu Macher in Scream (2022), and O'Connor having been cast in the upcoming Scream 7.
- Jenna Ortega and David Arquette starred together before Scream (2022) in Saving Flora (2018).
- Samara Weaving and Bella Thorne both starred in the 2017 Netflix film The Babysitter (2017), a horror comedy, who reprised their roles in the sequel, The Babysitter: Killer Queen (2020), who starred alongside Jenna Ortega, the latter appearing in the sequel.
- Lucy Hale and Tyler Posey starred together in Truth or Dare (2018).
- Giorgia Whigham and Dylan Minnette starred in the first season of the Netflix series 13 Reasons Why (2017-2020), with Whigham appearing in the first season as a minor role, with Bex Taylor-Klaus appearing in the show's second season. Both Tom Maden and Tom Everett Scott appeared as well, with Maden in a minor role, and Scott being in a recurring role.
- Sosie Bacon also starred as a romantic interest for Dylan Minnette's character.
- Drew Starkey as Hawkins from Season 3, starred in the 2022 Hellraiser remake alongside Brandon Flynn, who'd been one of the main characters in 13 Reasons Why and was Dylan Minnette's co-star as both played classmates turned adoptive brothers. The Hellraiser movies were referenced by Beth in "Ports in the Storm".
- Willa Fitzgerald and Mary McDonnell starred in the Netflix miniseries The Fall of the House of Usher (2023).
- Willa Fitzgerald and McKenna Grace will co-star in the upcoming film Regretting You (2025).
- Willa Fitzgerald and Santiago Segura star in the Netflix medical drama Pulse (2025), of which they co-star alongside Jessie T. Usher, Justina Machado, Arturo Del Puerto, and Jessica Rothe, with the latter four all appearing in other projects with actors and crew from the franchise.
- Usher co-starred with both Sosie Bacon and Kyle Gallner on Smile (2022), and with Jack Quaid on The Boys (2019-present).
- Machado having starred in Final Destination 2 (2003), alongside Tony Todd.
- Del Puerto starred in The Lincoln Lawyer (2022-), which stars Neve Campbell.
- Rothe, known for her role as Tree in the Happy Death Day films (2017-present), of which were directed by Christopher Landon, who was originally hired to direct the upcoming Scream 7.
- Tom Everett Scott and Alicia Silverstone starred in Diary of a Wimpy Kid: The Long Haul (2017), with Silverstone being the actress in-universe to have portrayed Tatum Riley in Stab, per Scream (2022), who in Scream (1996), was referenced via her first name only by Randy Meeks in response to Stu Macher saying "As if!", the catchphrase of character Cher Horowitz, who Silverstone portrayed in Clueless (1995).
- Notably, Silverstone's own co-star Paul Rudd, starred in Death of a Unicorn (2025), opposite Jenna Ortega.
- Luke Wilson and Selma Blair starred together in Legally Blonde (2001), alongside lead actress Reese Witherspoon as Elle Woods, with Wilson being the in-universe actor who portrays Billy Loomis in Stab, and Blair as Cici Cooper's (Sarah Michelle Gellar) friend of who's with her on the phone, in a voice role only and not physically seen, in Scream 2.
- Witherspoon had previously starred in Fear (1996) with Mark Wahlberg, who's the husband of Jenny McCarthy (Sarah Darling, Scream 3), and would star alongside Blair, Gellar, Joshua Jackson (Film Class Guy #2, Scream 2), and Ryan Phillipe in Cruel Intentions (1999), with Phillipe as Gellar's I Know What You Did Last Summer co-star, who'd later be Sandra Bullock's Crash (2004) co-star, who's referenced.
- Witherspoon also stars in the Apple TV series The Morning Show (2019-present) with Jennifer Aniston, notably Courteney Cox's co star from Friends (1994-2004).
- Jennifer Coolidge, co-star of Witherspoon, Wilson, and Blair in Legally Blonde and it's 2004 sequel (minus Blair), known for her role in the American Pie franchise (which'd she co-star with Mena Suvari, who appeared in Beauty Shop with Queen Latifah), would gain critical acclaim and awards for her role as Tanya McQuoid in the HBO series The White Lotus (2021-present), in it's first two seasons, with Parker Posey as Victoria Ratliff appearing in the third season, after Coolidge's departure.
- Lukas Gage and Sydney Sweeney appeared in Lotus's Season 1, who'd both appear on the HBO series Euphoria (2019-present), which stars Zendaya as the lead, who's Bella Thorne's friend and co-star from Shake It Up.
- Sweeney would star in Once Upon a Time in Hollywood (2019), alongside Mikey Madison. Sweeney also appeared in Madame Web (2024), of which she starred alongside Dakota Johnson, Celeste O'Connor and Emma Roberts. Sweeney also appeared in Anyone But You (2023) with Dermot Mulroney portraying her character's father.
- Gage would then star in Smile 2 (2024), with Kyle Gallner, and Companion (2025) with Jack Quaid. Gage previously starred with Thorne in Assassination Nation (2018), directed also by Sam Levinson, who'd also made Euphoria. Gage is also set to star in the upcoming film, Love Language, opposite Isabel May.
- Tony Revolori, who portrayed Jason Carvey in Scream VI, starred in the MCU Spider Man films (2017, 2019, 2021) alongside Tom Holland and Zendaya, the latter Thorne's friend and former castmate .
- Skeet Ulrich and Jamie Kennedy worked together in As Good as it Gets (1997).
- In all of the Scream movies, a stuntman is usually used for the role as Ghostface, except for parts when they reveal themselves. However, in Scream when Randy Meeks is watching Halloween (1978), and Ghostface appears behind him, that was actually Skeet Ulrich. He specifically asked if he could wear the mask for at least one scene.
- Laurie Metcalf and Jerry O'Connell appeared in The Big Bang Theory (2007-2019), starring as a mother-son duo Mary and Georgie.
- Both portrayed characters related to one of the protagonists of the show, Sheldon Cooper (portrayed by Jim Parsons), who shares the same last name as both Cici Cooper and Marnie Cooper from Scream 2 (former) and Scream 4 (latter) ironically.
- Anthony Anderson appears prominently in the Scary Movie franchise, appearing first in Scary Movie 3 (2003) and Scary Movie 4 (2006), with the first film of the series of which began as a parody of Scream, while also using its original title; as the latter franchise's main character Cindy Campbell, portrayed by Anna Faris, is a parody of Sidney Prescott & a play on Sidney's actress, Neve Campbell, playing on the first and last name of each.
- Tori Spelling, Jenny McCarthy, Queen Latifah, Anthony Anderson, Jerry O'Connell, and Tyler Posey all appeared in the Scary Movie franchise, with Spelling having appeared in Scary Movie 2 (2001), which parodies haunting movies, most famously The Exorcist (1973) of which Linda Blair was in. McCarthy, Anderson, and Latifah appear in the third film, with Anderson in both the third and fourth films, O'Connell only in the fourth, and Posey in the fifth.
- Jenna Ortega starred in the Netflix series You on it's second season as Ellie Alves, the younger sister of Delilah Alves, portrayed by Carmela Zumbado, the latter of who had portrayed Deputy Haverland in Season 1 of the TV series.
- Jenna Ortega starred in Ti West's X film (2022), the first of the X trilogy, of which she co-starred with Brittany Snow, known for her role as Chloe Beale in the Pitch Perfect films (2012-2017), of which she co-starred and portrayed the best friend of Bellas' head Aubrey Posen, portrayed by Anna Camp, who's been cast in the upcoming Scream 7.
- Camp would also star in the fifth and final season of You in 2025, which Ortega and Zumbado had starred in previously in the show's Season 2 (2019).
- Jenna Ortega and Leslie Grossman starred in the American comedy horror film by American rock band Foo Fighters, Studio 666 (2022), with Grossman being Emma Roberts' co-star on American Horror Story (starting with Cult as the seventh season (2017), and then primarily in the eighth season Apocalypse (2018), ninth season 1984 (2019), and the twelfth season Delicate (2023-24)).
- Will Forte, an actor in the 2022 film alongside Ortega, also provided voice acting in the 2020 animated film Scoob!, which previously starred McKenna Grace voicing young Daphne, with Forte also starred in The Laundromat (2019) opposite David Schwimmer and Sharon Stone; as well as in The Ridicolous 6 (2015), opposite Luke Wilson, in the 2018 film A Futile and Stupid Gesture with Joel McHale, in the film Keanu (2016) with Jordan Peele, in Booksmart (2019) with Mason Gooding, and The Watch (2012) with Vince Vaughn.
- Emma Roberts dyed her hair brown for the role of Jill Roberts in order to look more mysteriously than her being blonde. This last happened in Scream where Rose McGowan had to dye her blonde in order to differ her appearance to Neve Campbell.
- Kevin Williamson and Julie Plec who are the screenwriters and producers of Scream later worked on the television show The Vampire Diaries together.
- Sarah Michelle Gellar discusses Party of Five (1994-2000) with her friend. This show stars Neve Campbell and implies she exists separate from Sidney Prescott in a fourth wall break moment.
- This is similar to Carrie Fisher portraying someone who looks exactly like herself named Bianca Burnette in Scream 3, bitter that the one "who sleeps with George Lucas" got the part. In another wall-break moment, Bianca asks Gale asks her, "Or do you want me to tell you who you look like?" Gale smiles, knowing she means Courteney Cox.
- The Star Wars movies are also referenced in Scream 2, with Mickey (Timothy Olyphant) trying to state to Randy on sequels by mentioning The Empire Strikes Back (1980).
- Later on in Season 3 by Amir (C.J Wallace) stated Beth (Giorgia Whigham) having the Force, due to Beth mentioning Luke Skywalker crossing into the Dark Side.
- Rian Johnson, director of Star Wars: The Last Jedi (2017), stated as the director of Stab 8 (2021), titled Stab, in the fifth film, Scream (2022), with the death of Luke Skywalker and the trope of how former main characters in requels being killed after being brought back
- Summarized by Mindy Meeks-Martin, niece of Randy himself and the new horror expert, in Scream VI, with Luke's mentioned death having occurred ironically in The Last Jedi which Johnson directed, which's tied in to the poorly received requels commentary by fans and the motive for why Ghostface 8 (Richie Kirsch)/9 (Amber Freeman) committed the murders from the fifth film, in response to Stab 8, in meta-commentary fashion, as it tied into a rule of how expandable new and main characters are as stated by Mindy in Scream VI.
- Gale Weathers in Scream 2 mentions nude photos of her leaked, but it was just "her head" with Jennifer Aniston's body, her Friends co-star.
- Patrick Dempsey and Emma Roberts worked together in Valentine's Day (2010).
- Anna Paquin and Mikey Madison are the only actresses in the Scream franchise to have won Oscars for their performances in other projects, thus far.
- With Paquin before having appeared as a victim Rachel in Stab 7 in Scream 4 (for Best Supporting Actress in The Piano (1993) at the 1994 Academy Awards), while Madison won after appearing as Amber Freeman/Ghostface #8 in Scream (2022), the first actress to portray Ghostface killer to win a Best Actor/Actress Oscar (won for Best Actress for Anora (2024) at the 2025 Academy Awards).
- Laurie Metcalf is the first female Ghostface killer to have been nominated for an Oscar, for a Best Supporting Actress (like Paquin) for her perfomance in Lady Bird (2017) at the 2018 Academy Awards, nearly 20 years after her portrayal of Nancy Loomis/Ghostface #4 in Scream 2 (1997).
- Rebecca Gayheart auditioned for Tatum Riley, but the role went Rose McGowan. She later went on to play sorority sister Lois in Scream 2. Rose and Rebecca later starred together in Jawbreaker.
- David Arquette was the producer of Courteney Cox's television show Cougar Town.
- Hayden Panettiere, Skeet Ulrich, Matthew Lillard and Sarah Michelle Gellar worked together on the American animated television series Robot Chicken.
- Heather Matarazzo appeared on Roseanne which starred Laurie Metcalf.
- Sidney jokingly adds that Tori Spelling would play her in a movie and in Scream 2, Tori Spelling does indeed play her in Stab.
- Maureen Evans and her boyfriend, Phil Stevens, mention Sandra Bullock when going to see Stab.
- Bullock starred in Hope Floats (1998), alongside Mae Whitman, actress who'd co-star with Erik Knudsen in Scott Pilgrim vs. The World (2010), and with Bella Thorne in The DUFF (2015).
- Some of Sandra Bullock's various famous co-stars in her films (e.g. Keanu Reeves), are connected to via reference or other actors in the Scream franchise, who most recently co-starred with Channing Tatum in The Lost City (2022).
- Like Bullock, Tatum was name dropped and mentioned by Sherrie in Stab 6, a film-within-a film in Scream 4.
- With Sandra, alongside Matt Dillon and Ryan Phillipe having starred in Crash (2004), with Phillipe being in I Know What You Did Last Summer (1997), written by Kevin Williamson, starring alongside Sarah Michelle Gellar.
- With Sandra's co-star Matt Dillon as the former, also in Crash (2004), appearing in Wild Things (1998), which was referenced in Season 1, starring Neve Campbell and Kevin Bacon.
- Bullock starred with Matthew McConaughey in A Time to Kill (1995), previously was in Dazed and Confused (1993), who starred alongside Parker Posey in it.
- Starred in The Heat (2013) opposite Melissa McCarthy, who is Jenny McCarthy's cousin.
- Starred in Bird Box (2018), with her character's sister portrayed by Sarah Paulson, who'd appeared on American Horror Story (2011-present) alongside Emma Roberts.
- Both Bullock and Paulson were in Ocean's 8 (2018), which follows the Ocean's film series which starred George Clooney as Danny Ocean, of which Bullock's character is his sister.
- Kirby mentions the movie Piranha and A Nightmare on Elm Street. Wes Craven created the A Nightmare on Elm Street franchise. Scream 2 actor, Jerry O'Connell is in the movie Piranha 3D (2010) along with Steven R. McQueen who stars in The Vampire Diaries which was created by Scream writer, Kevin Williamson.
- Kym mentions to Beth buddy cop movies Rush Hour, 48 Hours, and Turner & Hooch, with Beth name drops Jackie Chan and Chris Tucker of the first film, mentioned. Later on Kym mentions Get Out (2017), directed by Jordan Peele, with Peele later in Scream (2022) also mentioned generally by Amber to Mindy, when discussing elevated horror.
- Chan starred in the 2010 remake-sequel The Karate Kid alongside Jaden Smith, the eldest son of Will Smith and Jada Pinkett Smith.
- Anthony Ruvivar starred in the 2021 TV series remake of Turner & Hooch.
- Amadeus Serafini starred in Hidden Strike (2023) opposite Jackie Chan and John Cena.
- Tucker starred in Friday (1995) opposite Ice Cube, would also appear in the music video for "You Rock my World" for Michael Jackson in 2001, being Paris Jackson's father, who portrayed Becky in Season 3.
- Tucker appears on American rapper Tupac's "California Love" music video in 1995, who as arguably the most famous of the 90s West Coast rappers, rivaled with East Coast rapper The Notorious B.I.G, who's C.J. Wallace's father, with C.J portraying Amir Ayoub, also cast of Season 3.
- Noah mentions the show Pretty Little Liars (2010-2017) in Season 1 to both Emma and Audrey. Lucy Hale, who was in Scream 4 as Sherrie in Stab 6 from the film-within-a film, played Aria Montgomery in the show.
- Ironically, while Channing Tatum was mentioned back in Scream 4, and Scarlett Johannsson in the first episode of Season 1, "Pilot", both actors then co-star in the 2024 film, Fly Me to the Moon.
- Mindy mentions the horror films Black Christmas, Child's Play, and Flatliners in the fifth film as rebooted, with the first film being referenced by Audrey and Gina in Season 2 by the original, and Kevin Bacon having starred in the last film of the list, in the 1990 film. She finished by listing examples of good requels, namely Saw, Terminator, Jurassic Park, Ghostbusters and Star Wars, with the first two films listed referenced, with Saw in the fourth film and Terminator in Scream 2 by Randy, with the latter being also referenced beginning with the second film, throughout the franchise's films and TV series as well.
- Mckenna Grace, of who's set to appear in Scream 7, has appeared in the two new Ghostbusters films, beginning with Ghostbusters: Afterlife (2021), alongside her co-star Paul Rudd (formerly Alicia Silverstone's co-star in Clueless (1995)), who appeared in Death of a Unicorn (2025) opposite Jenna Ortega. Interestingly, in the 2016 Ghostbusters, Melissa McCarthy starred, who's Jenny McCarthy's cousin.
- The Halloween franchise (1978-2022) is referenced, beginning in Scream (1996), which Randy mentioned in the first two films, to his niece Mindy in the sixth film, who during her explanation of the Rules, would also list other movie franchise characters such as: Laurie Strode, Ellen Ripley (Alien), Sally Hardesty (Texas Chainsaw Massacre), and Jigsaw (real name John Kramer, Saw), who'd list non-horror movie characters such as Tony Stark (aka Iron Man, Avengers, Marvel), James Bond (eponymous character), and Luke Skywalker (Star Wars). With Ripley being quoted by Randy in the second film, with Skywalker also referenced in said film; and in Season 3, of which sees the return of Ghostface, as Beth also mentions Skywalker & Hardesty (her brother) from The Texas Chainsaw Massacre.
- Brooke mentions the movie Gone Girl (2014), starring Rosamund Pike and Ben Affleck, the latter of who co-starred with Sandra Bullock in the romcom Forces of Nature (1999).
- Jack Quaid and McKenna Grace star in The Hunger Games film franchise (2012-present), based on the novels by Suzanne Collins, with Quaid in the first film (2012) as District 1 tribute, Marvel, with Grace set to portray Maysilee Donner, a District 12 tribute, in the sixth film Sunrise of the Reaping (2026).
- Audrey mentions to Will when assigned to him to partner as a project in class to not mention the pool scene from Wild Things (1998), starring Neve Campbell, Matt Dillon, and Kevin Bacon; latter being name dropped by Murphy to Sidney in Scream 2 (father of Sosie Bacon, who'd portrayed Rachel Murray from the TV series) just like Sandra Bullock is, who starred with Dillon in Crash (2004), 7 years after Scream 2, four after Scream 3 .
- Riley mentions the show The Walking Dead (2010-2022) to Noah in Season 1.
- Through a spin off-show, Tales of the Walking Dead (2022), Parker Posey would appear in the Walking Dead franchise.
- Cliff Curtis, who portrayed Travis Manawa in the first spin off and The Walking Dead's sister show Fear the Walking Dead (2015-2023), in it's first 3 seasons, appeared in Blow (2001), with Emma Roberts.
- Seth Branson in "Pilot", mentions TV shows American Horror Story and Bates Motel, with the former starring Emma Roberts beginning with it's third season, Coven (2013), and the latter show being a TV adaptation of Alfred Hitchcock's film Psycho (1960), as it's been referenced since both the original Scream (1996) and it's requel and fifth film, Scream (2022).
- The latter show mentioned by Branson starred actor Max Thieriot, who appeared in Nancy Drew (2007) alongside Emma Roberts, who portrayed the title character (based on detective in popular culture, akin to Sherlock Holmes), which fictional actress Jennifer Jolie uses sarcastically to refer to Gale Weathers in Scream 3.
- Both Freddie Highmore and Emma Roberts, former in Bates Motel and latter from AHS, are both indirectly connected through actor Johnny Depp, who starred with Highmore in Charlie and the Chocolate Factory (2005), portraying Willy Wonka; and in Blow (2001) as George Jung, drug lord, with Roberts playing his daughter.
- With the character of Norman Bates (portrayed by Anthony Perkins in 1960 to Vince Vaughn in the 1998 remake; Freddie Highmore in 2013; the actor of the 1960 character being the namesake of Deputy Perkins in Scream 4, portrayed by Anthony Anderson) name dropped by Billy to Sidney.
- In Scream VI, the name of victim Laura Crane, portrayed by Samara Weaving, is a reference to Psycho's infamous victim, Marion Crane, portrayed by Janet Leigh in 1960 and by Rihanna in 2017 from Bates Motel, (Leigh being Jamie Lee Curtis's mother, also a scream queen and from the Halloween franchise, Laurie Strode, who's been referenced since the first film, name-dropped in Scream 4/5), which Amber mimics the infamous shower to Sidney.
- Rose McGowan who portrayed Tatum Riley in the first movie, starred on an episode with Jenny McCarthy who plays Sarah Darling in Scream 3 on Charmed.
- Keke Palmer and Queen Latifah both co-starred in Barbershop 2: Back in Business (2004), alongside rapper Ice Cube, which Chris Tucker, actor from Rush Hour which Palmer's character Kym mentions, starred with Cube on Friday (1995).
- Anthony Anderson, Queen Latifah, Keke Palmer, and Tyga, the latter three involved in Season 3 (Latifah as third season's executive producer), the former from Scream 4, all have appeared in the Barbershop franchise alongside American rapper Ice Cube, which Anderson appeared first in the first and third films, Latifah and Palmer the second/third in the second film, and Tyga as the fourth appeared in the third film.
- Queen Latifah appeared in the Barbershop series spin off film Beauty Shop from 2005, starring Alicia Silverstone, Kevin Bacon, Mena Suvari, and Andie Macdowell.
- With Silverstone as the in-universe actress of Tatum Riley in Stab, indirectly being referenced by her first name by Randy in Scream, in response to Stu uttering her character Cher Horowitz's catchphrase "As if", from Clueless (1995), most notably.
- Bacon referenced by name by Murphy in Scream 2, father of an actress who is in the TV series. Interestingly, Macdowell would appear in Footloose (2011) a remake of the original 1984 film of the same name, of which Bacon was in.
- Silverstone and Suvari would appear in the FX American Horror Story series, of which Emma Roberts and Dermot Mulroney also appeared in, with Suvari, known for roles in Nowhere (1997), the American Pie franchise (1999-2020), and most famously American Beauty (1999), appeared as Elizabeth Short in Murder House (2011) and Apocalypse (2018), latter of which Roberts was in.
- Suvari, who appeared in the music video for "Teenage Dirtbag" by Wheatus, in Nowhere (1997), had starred alongside Heather Graham, the in-universe actress of Casey Becker in Stab, and Ryan Phillipe, who'd be Sarah Michelle Gellar's co-star in I Know What You Did Last Summer that same year, who'd later on, be Sandra Bullock's co-star in Crash (2004), with Bullock being referenced by name in Scream 2.
- Carlson Young had appeared in the Key & Peele skit "Substitute Teacher", with actor Keegan Michael-Key, with Jordan Peele as the latter half of the duo's sketch comedy show from Comedy Central, which aired from 2012 to 2015.
- Bella Thorne and Jenna Ortega were both former Disney Channel alums, with Thorne in Shake It Up (2010-2013) opposite actress Zendaya, to Ortega as the lead on the show Stuck in the Middle (2016-2018).
- Emma Roberts and Keke Palmer were both former Nickelodeon alums, with Roberts on Unfabulous (2004-2007), and Palmer on True Jackson, VP (2008-2011).
- Alicia Silverstone and Bella Thorne starred in American Horror Stories (2022-), spin-off of the main FX show American Horror Story (2011-) show, latter starring Emma Roberts.
- Kevin Smith, director and actor of Clerks (1995), friends of Wes Craven (who allowed for Smith to place poster of his film in the original Scream) who'd appeared alongside his duo of Jay and Silent Bob as a cameo in Scream 3, would cast Johnny Depp's daughter Lily-Rose Depp, alongside him in his film Tusk (2014), with Johnny having co-starred with Emma Roberts in Blow (2001).
- Erik Knudsen (Robbie) plays Lucas "Crash" Wilson in Scott Pilgrim vs. The World (2010) with Kieran Culkin as Wallace Wells, who is the brother of Rory Culkin (Charlie). Knudsen was also in the Saw movies, in Saw II, as the Saw franchise was previously mentioned by Trudie and Sherrie in Stab 6, (with Sherrie mentioning Saw IV), in Scream 4.
- The characters Jennifer Jolie and Angelina Tyler are named after Angelina Jolie and Jennifer Aniston.
- Tom Prinze is named after Freddie Prinze Jr., the husband of Scream 2 star Sarah Michelle Gellar. Both also starred in Scooby Doo together with Matthew Lillard (Stu).
- His first name could be a reference to actor Tom Cruise, first being referenced in Scream by Tatum Riley to Sidney Prescott on his film All the Right Moves, later by Mickey Altieri in Scream 2, alongside Derek Feldman, the latter actually singing a song from Cruise's film Top Gun.
- Josh Segarra appeared in PBS's The Electric Company (2009-2011) as Hector Ruiz, and who's co-star William Jackson Harper as Danny Rebus, is Chidi Anagonye in the NBC series The Good Place (2016-2020) with lead Kristen Bell as Eleanor Shellstrop.
- With Bell appearing as Chloe in Stab 7 in Scream 4, who's Stab film poster is shown in Scream VI, which Segarra stars in; of whose character shares the same first name, Danny, as his co-star Harper's character from Electric Company, ironically.
- Bell's (and Harper's) Good Place co-star Manny Jancito, also starred in Top Gun: Maverick (2022), notably starring Tom Cruise, actor who was mentioned in Scream and Scream 2. Jancito would also star in Bad Times at El Royale (2018) with Dakota Johnson (who would later star in Madame Web (2024) with Sydney Sweeney and Celeste O'Connor) who is set to star in Love Language opposite Lukas Gage and Isabel May.
- Drew Barrymore and Kristen Bell worked together in the movie Everybody Loves Whales (2012).
- Sarah Michelle Gellar and Rebecca Gayheart worked together in the film, Harvard Man (2001).
- Scott Foley worked on Courtney Cox's show Cougar Town for a couple of episodes.
- To keep Drew Barrymore crying and looking scared, Wes Craven kept telling her real life stories about animal cruelty. She is a keen animal lover in real life.
- Scott Foley appeared in both House and Scrubs, starring with Omar Epps in the former and Dave Franco in the latter, with Franco being Alison Brie's husband.
- Scott Foley and Portia De Rossi starred together in Scandal (2012-2018).
- Laurie Metcalf and John Karna starred together in Lady Bird (2017).
- Scott Foley and Skeet Ulrich have appeared in the Law & Order franchise.
- David Arquette and Rose McGowan starred together in the American comedy Ready to Rumble (2000).
- Everyone who has ever uttered the phrase "I'll be right back" has died. This obeys the "rules".
- Each film employs a red herring or two. In Scream, it is Neil Prescott. In Scream 2, it is Derek and Cotton. In Scream 3, it is John Milton and Angelina Tyler (though this came from script changes last minute, as she was intended to be a killer). In Scream 4, it is Judy Hicks and Trevor Sheldon, and in Scream (2022), it is Liv McKenzie.
- Scott Foley appeared in a Scream parody episode of Dawson's Creek with Joshua Jackson (who appeared in Scream 2). This scene was used in Scream (2022), where Tara watches it from the hospital. In Scream-universe context, it is Roman Bridger portraying the character in a brief stint as an actor.
- Neve Campbell (Sidney), Patrick Dempsey (Mark), Scott Foley (Roman), Laurie Metcalf (Nancy/Debbie), Heather Matarazzo (Martha), Brianne Tju (Riley), Dylan Minnette (Wes) Santiago Segura (Gustavo) and Jasmin Savoy Brown (Mindy) have all appeared on the medical drama Grey's Anatomy at some point.
- In Grey's Anatomy, Neve and Patrick portray siblings, but in Scream, they are romantically linked and later shown to be a married couple. Neve Campbell joked about this, upon discovering Mark was Sidney's husband in 2022. She also joked about playing his sibling after portraying "pseudo love interests" in 2012.[1]
- In Grey's Anatomy, Patrick's character is called Derek, who loathes his best friend, Mark for sleeping with his wife. On Scream, Sidney's previous love interest before Mark (Dempsey) was called Derek.
- Feeling bad about the line "With my luck they'd cast Tori Spelling", Neve Campbell sent Tori Spelling flowers and an apologetic card.
- The scene where Billy sneaks into Sidney's room in Scream is almost identical to the scene where Glen sneaks into Nancy's room in A Nightmare on Elm Street (1984).
- Emma Roberts co-starred with four other actors of who are connected to four actors from the Scream franchise, with actors in the projects which Roberts stared with also being connected to cast of the franchise via other actors and actresses.
- In We're the Millers (2013), starred with Will Poulter and Jennifer Aniston, as the former is in Death of a Unicorn (2025) opposite Jenna Ortega, and Aniston the latter, is notably Courteney Cox's co-star and friend from Friends (1994-2004).
- Starred in Nerve (2016) alongside Dave Franco, who is Alison Brie's husband, and with Brie being Roberts's co-star from Scream 4.
- Roberts's co-star Franco would also appear on 21 Jump Street (2012) and 22 Jump Street (2014), alongside Channing Tatum, actor who's mentioned in Scream 4, with Franco appearing in the former 2012 film alongside actor Johnny Depp, reprising his role from the TV show of the same name who'd starred with Roberts in Blow (2001).
- With Dave Franco appearing alongside Tatum, Depp and Ice Cube (who would appear with Tatum and Cube for the 2014 sequel), the latter of who appears in the Barbershop franchise (2002-), of who starred with both Keke Palmer and Queen Latifah in Barbershop 2 (2004), and with Tyga in Barbershop 3: The Next Cut (2016).
- Juliette Lewis also stars alongside Roberts and Franco in Nerve, of who's own role in Natural Born Killers (1994), opposite Woody Harrelson, having in the Scream 2 original script leak, referenced by Hallie McDaniel as one of the Ghostface killers as a source of motivation in reference to Billy Loomis naming Anthony Perkins as Norman Bates from Psycho (1960) as his source of motivation, or lack thereof, from the first Scream. Lewis would also star in From Tusk till Dawn (1996), directed by Robert Rodriguez, who in-universe directed the first Stab film
- In regards to Dave Franco, Lewis had co-starred with Johnny Depp, his co star from the 2012 film, in What's Eating Gilbert Grape (1993), as well as with Leonardo DiCaprio.
- Roberts's co-star Franco would also appear on 21 Jump Street (2012) and 22 Jump Street (2014), alongside Channing Tatum, actor who's mentioned in Scream 4, with Franco appearing in the former 2012 film alongside actor Johnny Depp, reprising his role from the TV show of the same name who'd starred with Roberts in Blow (2001).
- Starred in The Blackcoat's Daughter (2015) with Kieran Shipka, known for her role as Sabrina Spellman in Netflix's Chilling Adventures of Sabrina (2018-2020), who Mckenna Grace appeared as young Sabrina, of who's been cast in Scream 7.
- In the beginning of Scream (1996) when Casey's parents come and hear her choking on the phone, Casey's dad says "Listen, I want you to drive to the McKenzies and call the police." At the end of the movie Halloween (1978), Laurie Strode tells the two little kids she's babysitting to walk over to the McKenzie's house to call the police. In Halloween H20: 20 Years Later (1998), Laurie repeats something similar, telling her son and his girlfriend to go to the Beckers, a tie-in, as Kevin Williamson penned the original Halloween 7 script.
- Finally, in Scream (2022), Liv McKenzie is seen, a member of this family.
- Linda Blair, who portrays the possessed daughter, Regan MacNeil in The Exorcist appears in Scream (1996) as the Obnoxious Reporter. Jamie Lee Curtis also appears through archive footage of Halloween (1978). In Scream 4's callback and remake theme, Robbie references both in comparison to Sidney.
- The killer's costume in the Scream movies has come to be known as "Ghostface". When the costume's package is first shown to Sheriff Burke by Dewey, it is actually called "Father Death". The only time "Ghostface" is actually mentioned is by Tatum right before she dies, when she calls him "Mr. Ghostface".
- Naming the costume "Father Death" was a red herring clue to the possibility that Sidney's father, Neil, was the real killer.
- Billy is named after Sam Loomis, the name of two different protagonists in Psycho (1960) and Halloween (1978). His daughter is also homaged through this. She is Sam Loomis, going by Sam, and while Carpenter is her legal surname, she is Billy's daughter and a Loomis.
- Nancy Loomis is a blunt expy (short for exported character) of Pamela Voorhees. She shares identical motives with her, and both were mothers to a single child who turned out to be a killer.
- David Arquette and Emily Mortimer starred together in Foreign Affair (2003).
- Drew Barrymore and Timothy Olyphant play a realtor husband and wife on Netflix’s Santa Clarita Diet series (2017-2019).
- Their on-screen daughter, portrayed by Liv Hewson, also acts as a character of who's Jasmin Savoy Brown’s girlfriend on the TV series, Yellowjackets. Hewson has also acted alongside Mason Gooding in Let it Snow (2019).
- Barrymore and Olyphant's co-star Ethan Suplee later in the show appeared in Blow (2001), alongside Emma Roberts.
- Jack Quaid stars in Companion (2025) opposite Sophie Thatcher, an actress of who stars in Yellowjackets alongside Jasmin Savoy Brown.
- Jack Quaid's mother, actress Meg Ryan, is mentioned by name by Sidney Prescott in the original Scream.
- Jack Quaid as Hughie Campbell in the Amazon Prime series The Boys (2019-present), also starred alongside Jessie T. Usher as A-Train and Jensen Ackles as Soldier Boy, of who's co-stars were in projects with other actors of the Scream franchise.
- Quaid's co-star Usher was in Smile (2022) alongside Sosie Bacon and Kyle Gallner.
- Quaid's co-star Ackles, best known for his role as Dean Winchester in the CW show Supernatural (2007-2020), was in the show alongside Alexander Calvert, who portrayed Tom Martin/The Shallow Grove Slasher during the "Halloween/II" specials in Season 2.
- Despite his absence in The Boys spin off show Gen V, two actors of who portray two main characters from the spin off of Jack Quaid's main show, Jaz Sinclair and the late Chance Peromo, appeared in Netflix's Chilling Adventures of Sabrina (2018-2020), of which Mckenna Grace appeared in as a young Sabrina, her main and older counterpart portrayed by Kieran Shipka, with Grace having been cast in the upcoming Scream 7.
- Asa Germann, of who appears in Gen V alongside Mckenna Grace's Chilling co-stars Sinclair and Peromo, a co-star of Jack Quaid of The Boys, by association, has also been cast in Scream 7.
- Skeet Ulrich, Marisol Nichols, Lucy Hale, Mark Consuelos, and Mckenna Grace have all starred in the CW/Netflix shows related to the Riverdale franchise; with Ulrich, Nichols, and Consuelos in Riverdale, Hale as the title character of the show of the same name (Katy Keene, 2020), and Grace as a younger version of the titular Sabrina Spellman in Chilling Adventures of Sabrina, all based off the Archie Comics.
- Sarah Michelle Gellar starred as Helen Shivers in I Know What You Did Last Summer (1997) which was written by Kevin Williamson and came out the same year as Scream 2. Helen has a similar scene to Hallie McDaniel and Sidney Prescott when Mickey Altieri kills the officers protecting them and they became trapped. Helen is able to escape, but is ultimately killed by Ben Willis just like Hallie was killed by Mickey. Also, just like Randy Meeks, Helen is killed not far from bystanders.
Sarah Michelle Gellar as Helen Shivers in I Know What You Did Last Summer.
- Drew Barrymore and Carrie Fisher worked together in Charlie's Angels: Full Throttle (2003).
- Drew Barrymore starred in both of the original Y2K Charlie's Angels duology films (2000-2003), and Kristen Stewart in Charlie's Angels (2019), a remake, with Stewart originally being eyed for an opening victim role in Scream 4, but who'd declined, and stated how she couldn't emulate Drew's iconic opening scene as Casey from the original film[2].
- Drew Barrymore attended the 1995 VMAs on MTV, of which the famous musician fathers of VH1's Season 3 actors, C.J Wallace (as Amir Ayoub) and Paris Jackson (as Becky), had attended alongside Drew:
- Due to rapper The Notorious B.I.G, as C.J's father presenting the award for Best Dance Video to both singers Michael Jackson, Paris's father, and to Michael's sister and Paris's aunt, Janet Jackson, for their collaboration on the song "Scream" (which ironically would be the name of the first film of the franchise, of which Drew would star in just a year later), coincidentally, Drew was also the presenter of the namesake award of Paris's father, the Michael Jackson Video Vanguard Award.
- Leonora Scelfo and Nancy Anne Ridder would work together again after their cameo roles in Scream (1996), for the 2024 horror film, Tahoe Joe 2: The Sierra Nevada Bigfoot Conspiracy.
- Sean Grandillo starred in King Cobra (2016) alongside Alicia Silverstone, Molly Ringwald, Christian Slater, and James Franco, with each actor connected via others in the franchise.
- Silverstone was referenced by Randy Meeks indirectly and quoted by Stu Macher via her character Cher Horowitz' catchphrase "As if!" from Clueless (1995), in Scream, who in Scream (2022), was stated as in-universe as the actress who portrayed Tatum Riley in Stab (2021).
- Ringwald was offered the role of Sidney in the first film, but turned it down, with the role instead going on to be portrayed by Neve Campbell.
- Slater starred in True Romance (1993) with Patricia Arquette, who is David Arquette's sister, who would later co-star alongside both David and Courteney Cox in 3000 Miles to Graceland (2001).
- Franco is the older brother of Dave Franco, the latter who's the husband of Alison Brie, who portrayed Rebecca Walters in Scream 4.
- Sarah Michelle Gellar and Anthony Ruvivar worked together in Simply Irresistible (1999).
- Timothy Olyphant and Anthony Ruvivar appeared in A Perfect Getaway (2009)
- Sarah Michelle Gellar and Selma Blair, who portrayed Cici Cooper and voiced Cici's friend respectively in Scream 2, would go on to star together in Cruel Intentions (1999).
- Joshua Jackson also appeared in this film.
- Selma Blair and Nancy Anne Ridder worked together in Storytelling (2001).
- Jamie Kennedy and Omar Epps starred together in Trick (2019).
- David Arquette and Scott Foley reunited in The Storied Life Of A.J. Fikry (2022).
- Samara Weaving, Adam Brody, and Henry Czerny all starred together in the American horror movie Ready or Not (2019).
- Marisol Nichols and Skeet Ulrich worked together on the popular TV show Riverdale, which is based on the Archie Comics.
- Rory Culkin and Britt Robertson starred together in Jack Goes Home (2016).
- Tony Todd and Bex Taylor-Klaus starred together in Hell Fest (2018).
- Anthony Ruvivar and Jason Wiles starred together in the NBC series Third Watch (1999-2005)
- Brianne Tju and Liana Liberato starred in the TV series, Light As a Feather (2018-19).
- Brianne Tju and Dermot Mulroney starred together in Gone in the Night (2022), opposite Winona Ryder.
- With Ryder, known for her titular role as Lydia Deetz in the 1988 film Beetlejuice, reprised it in the 2024 sequel Beetlejuice Beetlejuice, as the mother of daughter Astrid, portrayed by Jenna Ortega.
- Timothy Olyphant and Marley Shelton both worked in The Perfect Getaway (2009) and Elektra Luxx (2010).
- ↑ https://www.eonline.com/news/491713/rejoice-veronica-mars-and-buffy-the-vampire-slayer-are-teaming-up-find-out-why
- ↑ https://www.independent.co.uk/arts-entertainment/films/news/kristen-stewart-drew-barrymore-scream-4-cameo-b2037219.html#:~:text=all%20the%20difference.-,Close,movie%20because%20it%20loves%20movies.%E2%80%9D